For relapsing malaria due to hypnozoites, what is used for radical cure after G6PD testing?

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Study for the Introduction to Parasitology Test. Use flashcards and multiple-choice questions, each question offers hints and explanations. Prepare for your exam thoroughly!

Multiple Choice

For relapsing malaria due to hypnozoites, what is used for radical cure after G6PD testing?

Explanation:
Relapsing malaria is driven by hypnozoites tucked away in the liver, so a radical cure must target those dormant liver stages. Primaquine is active against hypnozoites of P. vivax and P. ovale, making it the drug of choice for radical cure after confirming that G6PD function is normal. The reason G6PD testing matters is that primaquine can cause hemolytic anemia in people with G6PD deficiency, so only those with normal G6PD status should receive it. The other drugs shown don’t affect the liver stages: chloroquine and mefloquine target blood-stage parasites, and ivermectin isn’t used for malaria treatment. Therefore, primaquine is the best answer for radical cure after G6PD testing.

Relapsing malaria is driven by hypnozoites tucked away in the liver, so a radical cure must target those dormant liver stages. Primaquine is active against hypnozoites of P. vivax and P. ovale, making it the drug of choice for radical cure after confirming that G6PD function is normal. The reason G6PD testing matters is that primaquine can cause hemolytic anemia in people with G6PD deficiency, so only those with normal G6PD status should receive it. The other drugs shown don’t affect the liver stages: chloroquine and mefloquine target blood-stage parasites, and ivermectin isn’t used for malaria treatment. Therefore, primaquine is the best answer for radical cure after G6PD testing.

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