Leishmania parasites colonize which two types of hosts?

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Study for the Introduction to Parasitology Test. Use flashcards and multiple-choice questions, each question offers hints and explanations. Prepare for your exam thoroughly!

Multiple Choice

Leishmania parasites colonize which two types of hosts?

Explanation:
Leishmania has a two-host life cycle, needing both a vertebrate mammal and a sandfly vector to complete development. In the mammalian host, the parasite lives inside phagocytes, mainly macrophages, as intracellular amastigotes. In the sandfly, it colonizes the midgut as promastigotes, multiplying there before moving to the foregut and being transmitted to a new mammalian host. So the two primary colonization sites are the phagocytes of mammals and the intestinal tract (midgut) of Phlebotomine sandflies.

Leishmania has a two-host life cycle, needing both a vertebrate mammal and a sandfly vector to complete development. In the mammalian host, the parasite lives inside phagocytes, mainly macrophages, as intracellular amastigotes. In the sandfly, it colonizes the midgut as promastigotes, multiplying there before moving to the foregut and being transmitted to a new mammalian host. So the two primary colonization sites are the phagocytes of mammals and the intestinal tract (midgut) of Phlebotomine sandflies.

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